Rifampin ( Rifadin) may decrease the elimination of haloperidol, increasing the risk of side effects from haloperidol. Haloperidol is the first of the butyrophenone series of major antipsychotics. The tricyclic class of antidepressants for example:Ĭertain antihypertensive medications for example:Ĭarbamazepine ( Tegretol) may increase the elimination of Haldol, rendering the haloperidol less effective. oxycodone and acetaminophen ( Percocet).The narcotic class of pain medications and its derivatives for example: Haloperidol causes sedation, and sedation may be greater if haloperidol is taken with alcohol and other drugs that can cause sedation such as the benzodiazepine class of anti- anxiety drugs for example: Haloperidol also may cause abnormal heart beats, sudden death, seizures, decreases in red and white blood cells, and withdrawal symptoms.Įlderly patients with dementia-related psychosis and treated with antipsychotic drugs such as haloperidol are at an increased risk of death. The chemical designation is 4- 4- (p-chlorophenyl)-4-hydroxypiperidino-4'-fluorobutyrophenone and it has the following structural formula: Haldol (haloperidol) is available as a sterile parenteral form for intramuscular injection. Delirium and acute confusional states: Prevention, treatment, and prognosis. Haloperidol is the first of the butyrophenone series of major antipsychotics. Orthostatic hypotension causes patients to become dizzy upon arising from a lying or sitting position because of a drop in blood pressure. disintegrating tablet or haloperidol 2 to 10 mg orally For agitated patients not willing or able to take oral medications, we suggest olanzapine 5 to 10 mg intramuscularly (IM) or haloperidol 2 to 10 mg IM. Haloperidol may cause a condition called " orthostatic hypotension" during the early phase of treatment (first week or two). (DNP) to study the mode of complexation in search of an antidote to DNP. Other important side effects of haloperidol are: Key words 2,4-dinitrophenol, quinine, quinidine, haloperidol, trazodone.
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